Perinatal neuroimmunopathology: from experiment to clinic
Abstract
This review presents studies of the Laboratory of General and Perinatal Neuroimmunopathology of the Institute of General Pathology and Pathophysiology in modern areas of experimental neuroimmunopathology and new methods for diagnosis and treatment of perinatal CNS disorders associated with diabetes mellitus and autoimmune pathology. The review addresses the relationship between deviations in the content of maternal autoantibodies during pregnancy and nervous system abnormalities in newborns; the use of the Neuro-test technology for the in-hospital monitoring of the management of children with severe organic lesions of the nervous system; long-term neurological outcomes in children born to mothers with gestational diabetes mellitus (GDM), one of the most common complications of pregnancy.