Ways of correction immune homeostasis changes during pregnancy assessing the state of health of offspring

  • S. G. Morozov Institute of General Pathology and Pathophysiology, Moscow, Russian Federation
  • E. N. Kozhevnikova Institute of General Pathology and Pathophysiology, Moscow, Russian Federation
  • O. B. Kadasheva N.E.Bauman City Clinical Hospital №29, Moscow, Russian Federation
  • N. P. Petkevich Institute of General Pathology and Pathophysiology, Moscow, Russian Federation
  • A. V. Lobanov Branch of the M.M.Shemyakin –Yu.A.Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Pushchino of Moscow Region, Russian Federation
  • A. N. Murashev Branch of the M.M.Shemyakin –Yu.A.Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Pushchino of Moscow Region, Russian Federation
  • A. A. Sidyakin N.E.Bauman City Clinical Hospital №29, Moscow, Russian Federation
  • I. A. Zakharova Institute of General Pathology and Pathophysiology, Moscow, Russian Federation
  • I. E. Gribova N.E.Bauman City Clinical Hospital №29, Moscow, Russian Federation
  • V. M. Inshakova Institute of General Pathology and Pathophysiology, Moscow, Russian Federation
Keywords: immunoneurophysiology

Abstract

It has been shown that children born to mothers with low levels of aATs to MBP, protein S100, ASVR-C, MR-C during pregnancy, who did not receive immunotherapy, are more likely to be born prematurely, in asphyxia, with lower birth rates (body weight, growth, Apgar score), which requires their long-term observation in the maternity hospital (up to 2 weeks) or transfer to children's hospitals with diagnoses such as PPNS, IUGR, IVH, prematurity. In children from the comparison group, changes in NSH are more often recorded, they are more pronounced and require a longer time for their compensation, therefore, these children are more often observed by a neurologist with diagnoses such as PPNS or hypoxic-ischemic CNS damage, episyndrome, etc. Children in this group more often suffer from pneumonia due to the failure of the immune system.

Published
2023-03-06
How to Cite
Morozov, S. G., Kozhevnikova, E. N., Kadasheva, O. B., Petkevich, N. P., Lobanov, A. V., Murashev, A. N., Sidyakin, A. A., Zakharova, I. A., Gribova, I. E., & Inshakova, V. M. (2023). Ways of correction immune homeostasis changes during pregnancy assessing the state of health of offspring. Patogenez (Pathogenesis), 12(3), 20-26. Retrieved from https://pathogenesis.pro/index.php/pathogenesis/article/view/618
Section
Original investigations