Nanosized dosage forms as delivery systems for proteins

  • A. P. Kaplun Institute of General Pathology and Pathophysiology, Moscow, Russian Federation; Moscow State University of Fine Chemical Technology. MV Lomonosov, Moscow, Russian Federation
  • V. V. Krasilnikova Moscow State University of Fine Chemical Technology. MV Lomonosov, Moscow, Russian Federation
  • A. A. Kubatiev Institute of General Pathology and Pathophysiology, Moscow, Russian Federation
Keywords: vaccines, liposomes, nanocrystals, nanoparticles, passive targeting, emulsions

Abstract

Proteins as drugs have serious disadvantages: they quickly hydrolyzed after administration; they can cause undesired immune responses. An important way to overcome these shortcomings is both modify them, or the incorporation into micro- or nanoparticles. The review on the basis of specific examples are considered basic principles of modification and encapsulation of proteins, as well as the effects obtained from such manipulations.

Published
2023-05-23
How to Cite
Kaplun, A. P., Krasilnikova, V. V., & Kubatiev, A. A. (2023). Nanosized dosage forms as delivery systems for proteins. Patogenez (Pathogenesis), 11(2), 4-16. Retrieved from https://pathogenesis.pro/index.php/pathogenesis/article/view/667
Issue
Vol. 11 No. 2 (2013): Патогенез
Section
Reviews