Toxicity studies nanodispersions spherical amorphous nanoparticles of birch bark triterpenoids in vitro

  • T. I. Ignashkova Institute of General Pathology and Pathophysiology, Moscow, Russian Federation
  • S. O. Mironova Moscow State University of Fine Chemical Technology. MV Lomonosov, Moscow, Russian Federation
  • L. A. Gavrilova Moscow State University of Fine Chemical Technology. MV Lomonosov, Moscow, Russian Federation
  • A. A. Moskovtsev Institute of General Pathology and Pathophysiology, Moscow, Russian Federation
  • A. P. Kaplun Institute of General Pathology and Pathophysiology, Moscow, Russian Federation; Moscow State University of Fine Chemical Technology. MV Lomonosov, Moscow, Russian Federation
  • V. A. Yurkiv Institute of General Pathology and Pathophysiology, Moscow, Russian Federation
  • V. I. Shvets Institute of General Pathology and Pathophysiology, Moscow, Russian Federation
  • A. A. Kubatiev Institute of General Pathology and Pathophysiology, Moscow, Russian Federation
Keywords: cytotoxicity, flow cytometry, hemolytic activity, HeLa, Jurkat, the MTT test, spherical amorphous nanoparticles

Abstract

Spherical amorphous nanoparticles of birch bark triterpenoids, promising carriers of hydrophobic substances, were tested for toxicity on two types of cells HeLa and Jurkat. These nanoparticles do not exhibit cytotoxic effects under the studied concentrations (up to 512 ug/ml).

Published
2023-05-23
How to Cite
Ignashkova, T. I., Mironova, S. O., Gavrilova, L. A., Moskovtsev, A. A., Kaplun, A. P., Yurkiv, V. A., Shvets, V. I., & Kubatiev, A. A. (2023). Toxicity studies nanodispersions spherical amorphous nanoparticles of birch bark triterpenoids in vitro. Patogenez (Pathogenesis), 11(2), 42-45. Retrieved from https://pathogenesis.pro/index.php/pathogenesis/article/view/671
Issue
Vol. 11 No. 2 (2013): Патогенез
Section
Original investigations