Ultrastructural analysis of the papillary muscle changes in heart in modeling of late-stage type I diabetes

Authors

  • A. V. Volodina Institute of General Pathology and Pathophysiology, Moscow, Russian Federation
  • L. P. Kobozeva Institute of General Pathology and Pathophysiology, Moscow, Russian Federation
  • O. M. Pozdnyakov Institute of General Pathology and Pathophysiology, Moscow, Russian Federation

Keywords:

experimental diabetes mellitus type I, myocardium, diabetic microangiopathy

Abstract

Electron microscopic study of the papillary muscles of the heart in rats with streptozotocin model of type I diabetes revealed widespread changes in cardiomyocytes, their contractile elements, mitochondria as well as intercalated disks. In blood capillaries found degenarativ-destructive changes of endolhelial cells. In general, the changes should be considered as microangiopathy.

Downloads

Published

2023-05-26

Issue

Vol. 12 No. 2 (2014): Патогенез

Section

Original investigations

How to Cite

1.
Volodina AV, Kobozeva LP, Pozdnyakov OM. Ultrastructural analysis of the papillary muscle changes in heart in modeling of late-stage type I diabetes. Патогенез. 2023;12(2):58-60. Accessed April 30, 2026. https://pathogenesis.pro/index.php/pathogenesis/article/view/628