The healing of thermal burns on the skin in experimental phototherapy
Abstract
The studies dedicated to the efficacy of skin wound phototherapy and pathogenetic substantiation of this
method are in sufficient. The aim of this work was to assess the healing effect of the polychromatic polarized
incoherent light (the "BIOPTRON compact" device) and laser red wave range (AZOR-02) to the standard thermal skin wound. Methods. The 3rd and 4th-degree skin burn wounds with the size of 24 sm2 were caused on the lateral body surface in rabbits and then treated with phototherapy. The course of treatment was performed by a daily irradiation during 10 days, starting from the stage of proliferation, i.e. on the 5th day after wounding. As evaluation criteria, the hematological, biochemical, morphological, and planimetric indicators were used. Results. No significant differences in the values of hematological parameters were found. At the same time, the differences between irradiated and non-irradiated animals by almost all other indicators were statistically significant. The morphological and planimetric study showed significant acceleration of the regeneration process in both types of light exposure, but the wound healing effect of the laser light of red wave length range was more pronounced than in the treatment by polarized light. Conclusion. Received data allowed to conclude that, in cause of ther maltreatment of skin wounds, optical polarized light and especially laser irradiation of red spectrum have a positive effect on activating of proliferation of macrophagal and fibroblastic cell branches, thus accelerating burn wound healing and preventing the transition of inflammation from acute to chronic form.
