Study of FRSN cells migration under the conditions of continuous low flow

  • A. A. Moskovtsev Institute of General Pathology and Pathophysiology, Moscow, Russia; Russian Medical Academy of Continuing Vocational Education, Moscow, Russia
  • D. V. Kolesov Institute of General Pathology and Pathophysiology, Moscow, Russia
  • A. N. Mylnikova Institute of General Pathology and Pathophysiology, Moscow, Russia; D.I. Mendeleev Russian University of Chemical Technology, Moscow, Russia
  • A. A. Kubatiev Institute of General Pathology and Pathophysiology, Moscow, Russia; Russian Medical Academy of Continuing Vocational Education, Moscow, Russia
DOI: https://doi.org/10.25557/2310-0435.2018.04.144-147
Keywords: fibroblasts, mesenchymal stromal cell, migration, microfluidics, shear stress

Abstract

The fluid flow exerts a significant effect on most cells in the body. This effect can involve cell migration under the action of shear stress or nutrient gradient. FRSN mesenchymal stem cells were cultured under the action of a constant fluid flow of low intensity in a microfluidic chip. The study of cell migration at different stages of adhesion was performed under the action of flow in different areas of the chip. Significant cell movements in a stick-slip mode along the flow direction were observed.

Published
2019-01-25
How to Cite
Moskovtsev, A. A., Kolesov, D. V., Mylnikova, A. N., & Kubatiev, A. A. (2019). Study of FRSN cells migration under the conditions of continuous low flow. Patogenez (Pathogenesis), 16(4), 144-147. https://doi.org/10.25557/2310-0435.2018.04.144-147
Issue
Vol. 16 No. 4 (2018): Pathogenesis
Section
Brief reports