Активность лейкоцитарной эластазы и альфа-1 протеиназного ингибитора у больных с атопическим дерматитом

M. V. Tarasova; M. V. Ovsyannikov; E. N. Volkova

doi:10.25557/2310-0435.2018.04.153-156

Activities of leukocyte elastase and alpha-1 proteinase inhibitor in patients with atopic dermatitis

M. V. Tarasova Institute of General Pathology and Pathophysiology, Moscow, Russia
M. V. Ovsyannikov Rostov State Medical University, Rostov-on-Don, Russia
E. N. Volkova Institute of General Pathology and Pathophysiology, Moscow, Russia

DOI: https://doi.org/10.25557/2310-0435.2018.04.153-156

Keywords: atopic dermatitis, leukocyte elastase, α1-proteinase inhibitor

Abstract

Summary. Leukocyte elastase activity has been shown to be increased in patients with atopic dermatitis and to correlate with the disease severity. However, this increase is not always accompanied by an adequately increased activity of the α1-proteinase inhibitor (α1-PI). Evidence suggest that the decreased α1-PI activity is an unfavorable prognostic sign of changes in BP that contribute to further progression of the destructive process.

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Published

2018-12-11

How to Cite

Tarasova, M. V., Ovsyannikov, M. V., & Volkova, E. N. (2018). Activities of leukocyte elastase and alpha-1 proteinase inhibitor in patients with atopic dermatitis. Patogenez (Pathogenesis), 16(4), 153-156. https://doi.org/10.25557/2310-0435.2018.04.153-156