Allelic Polymorphism of the Genes of Estrogen Metabolism Enzymes in case of Genital Endometriosis

  • K S Kublinskiy Siberian State Medical University, Russia, 634050, Tomsk, 2 Moskovsky trakt, e-mail: rector@ssmu.ru
  • V V Novitskiy Siberian State Medical University, Russia, 634050, Tomsk, 2 Moskovsky trakt, e-mail: rector@ssmu.ru
  • O I Urazova Siberian State Medical University, Russia, 634050, Tomsk, 2 Moskovsky trakt, e-mail: rector@ssmu.ru
Keywords: genital endometriosis, allelic polymorphism of the genes of estrogen metabolism enzymes

Abstract

Up-to-date molecular genetic research methods have revealed that women predisposed to genital endometriosis possess Allele G and Genotypes AG and GG of the polymorphic option 4889G of the CYP1A1 gene as well as Allele A and Genotypes CA and AA of the polymorphic option C-734A of the CYP1A2 gene. The polymorphism of the promoter regions of the SULT1A1 (G-638A) and SULT1E1 (C-174T) genes is not associated with genital endometriosis in women.

Published
2015-09-30
How to Cite
Kublinskiy, K. S., Novitskiy, V. V., & Urazova, O. I. (2015). Allelic Polymorphism of the Genes of Estrogen Metabolism Enzymes in case of Genital Endometriosis. Patogenez (Pathogenesis), 13(3), 41-44. Retrieved from https://pathogenesis.pro/index.php/pathogenesis/article/view/32
Issue
Vol. 13 No. 3 (2015): Pathogenesis
Section
Original investigations