Understanding the mechanism of tumor regression

Abstract

The current understanding of the nature of cancer is being questioned, and another explanation of the nature of this disease has been proposed. The mechanism of cancer is atavistic. It emerged in the Precambrian Metazoa, which were sedentary and colonized. This mechanism provided them with a means to adapt to seasonal changes in the environment. The developing kidneys of these animals preparing for diapause were the evolutionary precursors of a malignant tumor. The destruction that occurred in their kidneys when preparing for diapause was the evolutionary predecessor of the tumor destruction in the human body that occurs during cancer regression. Resorption of diapause-preparing kidneys was an evolutionary precursor to tumor regression. Tumor regression is rare and therefore difficult to study. Thus, this phenomenon should not be investigated in highly organized animals or in humans, but in colonized ascidians. Having understood how the mechanism of resorption of their kidneys functions when preparing for diapause, it will be easier to understand the mechanism of tumor regression. In plants, buds preparing for dormancy are sometimes also destroyed. Studying this process can similarly help decipher the mechanism of tumor regression.