Lipoproteins in blood plasma and variability of the intima-media thickness of the carotid arteries: comparative analysis of the Moscow and Paris population

  • E V Chernova Institute of General Pathology and Pathophysiology, Russian Academy of Sciences, Moscow 125315
  • T V Kirichenko for Atherosclerosis Research, Skolkovo Innovative Center, Moscow 121609
  • V A Orekhova Cardiology Research and Production Complex, Moscow, 121500
  • N A Nikitina Cardiology Research and Production Complex, Moscow, 121500
  • V P Карагодин Institute for Atherosclerosis Research, Skolkovo Innovative Center, Moscow 121609
  • A N Orekhov Institute for Atherosclerosis Research, Skolkovo Innovative Center, Moscow 121609
  • P Giral Dyslipidemia and Atherosclerosis Research Unit, INSERM UMR-S939, and University of Pierre and Marie Curie, Pitie-Salpetriere University Hospital, Paris
  • I A Sobenin Institute of General Pathology and Pathophysiology, Russian Academy of Sciences, Moscow 125315
Keywords: atherosclerosis; variability; cardiovascular risk factors; carotid intima-media thickness

Abstract

This population-based international cross-sectional study included 1200 participants without clinical manifestations of atherosclerosis from the Russian and French populations. To assess the susceptibility to the development of atherosclerosis, an ultrasonic evaluation of common carotid arteries was used. It has been analyzed the variability of carotid intima-medial thickness (cIMT) in two samples of participants with an increased risk of atherosclerotic diseases from Paris and Moscow. The role of traditional risk factors such as age, body mass index, lipid profile, in the formation of increase of cIMT has been studied. The most expressed predictive ability in susceptibility to atherosclerosis was the age and the level of low density lipoprotein cholesterol (LDL).

Published
2015-11-30
How to Cite
Chernova, E. V., Kirichenko, T. V., Orekhova, V. A., Nikitina, N. A., КарагодинV. P., Orekhov, A. N., Giral, P., & Sobenin, I. A. (2015). Lipoproteins in blood plasma and variability of the intima-media thickness of the carotid arteries: comparative analysis of the Moscow and Paris population. Patogenez (Pathogenesis), 13(4), 62-67. Retrieved from https://pathogenesis.pro/index.php/pathogenesis/article/view/45
Section
Original investigations