Influence of Dendritic Cells microenvironment on their role in inflammatory processes of atherogenesis

  • V. P. Karagodin Institute for Atherosclerosis Research, Skolkovo Innovative Center, Moscow, Russian Federation; Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, Russian Federation
  • Yu. V. Bobryshev Institute of General Pathology and Pathophysiology, Moscow, Russian Federation
  • D. A. Chistiakov Department of Medical Nanobiotechnology, Pirogov Russian State Medical University, Moscow, Russian Federation
  • A. N. Orekhov Institute for Atherosclerosis Research, Skolkovo Innovative Center, Moscow, Russian Federation; Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow, Russian Federation
Keywords: dendritic cells, atherosclerosis, inflammation, regulatory T-cells, subsets of DC

Abstract

The review deals with the different aspects of dendritic cells (DCs) in atherogenesis. Implementation of the effector functions of dendritic cells, expressed either in activation or suppression of immune responses, depends on their tissue microenvironment. The balance between inflammatory and antiinflammatory effects of dendritic cells is mediated by regulatory T-cells as well. DC phenotypes are described for mature and precursor cells.

Published
2023-05-26
How to Cite
Karagodin, V. P., Bobryshev, Y. V., Chistiakov, D. A., & Orekhov, A. N. (2023). Influence of Dendritic Cells microenvironment on their role in inflammatory processes of atherogenesis. Patogenez (Pathogenesis), 12(2), 20-26. Retrieved from https://pathogenesis.pro/index.php/pathogenesis/article/view/622
Issue
Vol. 12 No. 2 (2014): Патогенез
Section
Reviews