Cytoarchitecture of red blood cells and platelets in patients with arterial hypertension with dyslipidemia

Abstract

The aim of this study was to establish the characteristics of cellular composition of erythrocytes and platelets in patients with arterial hypertension with dyslipidemia. Under the supervision of patients with arterial hypertension were 380 1–2-degree, risk II b 4 types of dyslipidemia patients, average age. The monitoring group presented 26 healthy volunteers of a similar age. In patients with a combination of arterial hypertension with dyslipidemia is weakening and plasma antioxidant of cytoplasm of erythrocytes and platelets activation of lipid peroxidation, resulting in the alteration of their membrane structures inside and out. In patients with arterial hypertension with dyslipidemia revealed increased cytoarchitecture changes of erythrocytes and platelets. At the basis of violations found are negative shifts in the lipid metabolism, lipid peroxidation, activation of the plasma membrane and the uniform of the blood, its receptor, and cytoplasmic changes.