Regeneration in experimental stroke. Effect of platelets

Abstract

The severity of the problem of stroke stimulates its intensive development on experimental models. The attention of researchers engaged in this work is attracted by rapidly accumulating evidence of recent years on the regulatory role of plate lets in in flammatory processes, angiogenesis, regeneration and neuroprotection. Attempts are undertaken to use platelets or its microparticles as a therapeutic agent for stroke. These attempts are examined in the review. In search and presentation of the literature, the author was guided by the idea that functional expression of brain regeneration is provided by restoration and rearrange of damaged neural networks. It can happen to renovation of the new neurons instead of dead or without it by means of development of fibrous structures, neuroglia and circulation.