Exosomes in intercellular relationships

  • A. A. Paltsyn Institute of General Pathology and Pathophysiology, Moscow, Russian Federation; Russian Medical Academy of Continuing Vocational Education, Moscow, Russian Federation http://orcid.org/0000-0001-9686-8995
  • N. B. Sviridkina Institute of General Pathology and Pathophysiology, Moscow, Russian Federation
Keywords: exosome, receptor, membrane, intercellular interactions

Abstract

Since 1981, exosomes have been called 30-100 nm vesicles enclosed in a cell membrane, which were found in sediments of many body fluids. Later, exosomes were found to contain various types of proteins, RNA, and even DNA. Exosomes formed by one cell type fuse with cells of another type and transmit their contents to them as a signal. The fusion is not random, but in consistency with receptors on the membranes of exosome and recipient cell. Exosomes are a tool for regulated intercellular communications.

Published
2023-03-01
How to Cite
Paltsyn, A. A., & Sviridkina, N. B. (2023). Exosomes in intercellular relationships. Patogenez (Pathogenesis), 21(1), 79-82. https://doi.org/10.25557/2310-0435.2023.01.79-82