Ultrastructural analysis of the papillary muscle changes in heart in modeling of late-stage type I diabetes

  • A. V. Volodina Institute of General Pathology and Pathophysiology, Moscow, Russian Federation
  • L. P. Kobozeva Institute of General Pathology and Pathophysiology, Moscow, Russian Federation
  • O. M. Pozdnyakov Institute of General Pathology and Pathophysiology, Moscow, Russian Federation
Keywords: experimental diabetes mellitus type I, myocardium, diabetic microangiopathy

Abstract

Electron microscopic study of the papillary muscles of the heart in rats with streptozotocin model of type I diabetes revealed widespread changes in cardiomyocytes, their contractile elements, mitochondria as well as intercalated disks. In blood capillaries found degenarativ-destructive changes of endolhelial cells. In general, the changes should be considered as microangiopathy.

Published
2023-05-26
How to Cite
Volodina, A. V., Kobozeva, L. P., & Pozdnyakov, O. M. (2023). Ultrastructural analysis of the papillary muscle changes in heart in modeling of late-stage type I diabetes. Patogenez (Pathogenesis), 12(2), 58-60. Retrieved from https://pathogenesis.pro/article/view/628
Issue
Vol. 12 No. 2 (2014): Патогенез
Section
Original investigations