The role of apoptosis in impaired cellular adaptation in the oral cavity

  • Iu. I. Shramko Order of the Red Banner of Labor S.I. Georgievsky Medical Institute of the V.I. Vernadsky Crimean Federal University, Simferopol, Russian Federation http://orcid.org/0000-0003-4946-7317
  • A. V. Kubyshkin Order of the Red Banner of Labor S.I. Georgievsky Medical Institute of the V.I. Vernadsky Crimean Federal University, Simferopol, Russian Federation http://orcid.org/0000-0002-1309-4005
  • L. H. Duryagina Order of the Red Banner of Labor S.I. Georgievsky Medical Institute of the V.I. Vernadsky Crimean Federal University, Simferopol, Russian Federation http://orcid.org/0000-0003-2110-1321
  • N. A. Ivashchenko Order of the Red Banner of Labor S.I. Georgievsky Medical Institute of the V.I. Vernadsky Crimean Federal University, Simferopol, Russian Federation http://orcid.org/0000-0002-4960-9912
  • C. O. Tarimov Order of the Red Banner of Labor S.I. Georgievsky Medical Institute of the V.I. Vernadsky Crimean Federal University, Simferopol, Russian Federation http://orcid.org/0000-0001-6246-3551
  • U. R. Kempinskaya Order of the Red Banner of Labor S.I. Georgievsky Medical Institute of the V.I. Vernadsky Crimean Federal University, Simferopol, Russian Federation http://orcid.org/0009-0003-2256-6339
  • A. S. Mukhina Order of the Red Banner of Labor S.I. Georgievsky Medical Institute of the V.I. Vernadsky Crimean Federal University, Simferopol, Russian Federation http://orcid.org/0009-0005-6164-0698
DOI: https://doi.org/10.25557/10.25557/2310-0435.2024.03.13-19
Keywords: apoptosis, markers of apoptosis, cellular adaptation

Abstract

The objective of this review is to study the role of apoptosis in the processes of cellular adaptation in the oral cavity based on the analysis of data published in the modern medical scientific literature. The review includes data from foreign and domestic studies for the last 20 years. The analysis of data on the identification of the causes and mechanisms of apoptosis in hypo- and hyperbiotic processes, as well as in the development of malignant neoplasms in the oral cavity, is presented. It has been revealed that there are a number of cellular adaptation specificities in the oral mucosa, which in each case have specific to a particular factor sign of apoptosis. The role of apoptosis in the development of atrophy in the oral cavity because of dental prosthetics remains poorly studied.

Published
2024-10-09
How to Cite
Shramko, I. I., Kubyshkin, A. V., Duryagina, L. H., Ivashchenko, N. A., Tarimov, C. O., Kempinskaya, U. R., & Mukhina, A. S. (2024). The role of apoptosis in impaired cellular adaptation in the oral cavity. Patogenez (Pathogenesis), 22(3), 13-19. https://doi.org/10.25557/10.25557/2310-0435.2024.03.13-19
Issue
Vol. 22 No. 3 (2024): Pathogenesis
Section
Reviews