Immunological mechanisms of the pathogenesis of herpesvirus infection involving lymphocyte-platelet aggregates and polymorphic immune response molecules – IL-2(T330G) on the example of chickenpox (literature review)

Keywords: immunological mechanisms, pathogenesis, herpesvirus infection, lymphocyte-platelet adhesion, chickenpox, interleukin-2, IL-2(T330G)

Abstract

The aim is to evaluate the degree of involvement of lymphocyte-platelet interactions in carriers of IL-2(T330G) SNP in the immunological mechanisms of the pathogenesis of herpes virus infection using the example of chickenpox. Based on the analysis of modern literature sources, the role of lymphocyte-platelet aggregates has been determined and a conceptual scheme of their involvement in the immunopathogenesis of chickenpox in carriers of SNP IL-2(T330G) has been proposed.

Published
2025-09-26
How to Cite
Krivolutskaya, T., Gurina, O., Tsygan, V., Gumilyevskaya, O., Lemeshchenko, A., & Makarov, A. (2025). Immunological mechanisms of the pathogenesis of herpesvirus infection involving lymphocyte-platelet aggregates and polymorphic immune response molecules – IL-2(T330G) on the example of chickenpox (literature review). Patogenez (Pathogenesis), 23(3), 4-10. https://doi.org/10.48612/path/2310-0435.2025.03.4-10